- Medicxi Announces €500 Million Fund V
Nov 14, 2025
New fund will continue Medicxi's successful asset-centric company creation and investment strategy.
LONDON, Nov. 14, 2025 /PRNewswire/ -- Medicxi, a leading European life sciences venture capital firm, today announced the closing of Medicxi V, a €500 million fund dedicated to building and backing innovative biotechnology companies with clear product visions to transform patient care. The oversubscribed fund closed with strong support from existing limited partners and a select group of new institutional investors. The Fund will focus on Medicxi's pioneering asset-centric investment model.
Medicxi has created 16 new companies, delivered over 20 positive clinical data readouts and has realised over $1 billion across its portfolio since its last fundraise, including from investments in Vaxcyte, Merus and Abivax, and the acquisitions of ViceBio (Sanofi), Versanis Bio (Eli Lilly) and ProfoundBio (Genmab).
Medicxi V will continue the firm's focus on supporting drug hunters and entrepreneurs in creating asset-focused biotechnology companies to deliver transformative therapies for patients. The Fund will also invest in existing companies at all stages of development that align with Medicxi's asset-centric value creation strategy.
"Medicxi's longstanding success has been founded on its unique ties to leading global pharmaceutical companies and its world-class team of drug hunters and clinicians," said Francesco De Rubertis, Co-founder and Partner at Medicxi. "The new €500 million fund will enable Medicxi to provide the critical capital, expertise and experience to deliver transformative therapies for patients."
"Medicxi's differentiated, capital-efficient investment strategy is rapidly scaling and we have now raised six funds in the last 10 years, totalling over €2.0 billion," said Giovanni Mariggi, Co-founder and Partner at Medicxi. "We are extremely grateful for the support that we have received from our existing and new limited partners, and we are excited to continue investing in cutting-edge science and accelerating the discovery of life-changing medicines for patients."
Medicxi also announced that Shyam Masrani has been promoted to Partner. Masrani led Medicxi's investments in Merus and ProfoundBio, and currently serves on the boards of Acera Therapeutics, T-CypherBio and Petalion Therapeutics. The investing partners in Fund V are Francesco De Rubertis, Giovanni Mariggi, Nick Williams and Shyam Masrani.
Notes to Editors
About Medicxi
Medicxi is a healthcare-focused investment firm with the mission to create and invest in companies across the full drug development continuum. Leveraging deep expertise in drug development and company creation spanning over two decades, Medicxi invests in early and late-stage therapeutics with a product vision that can fulfil a clear unmet medical need. For more information, please visit: www.medicxi.com.
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- Are Medical Stocks Lagging Abivax SA Sponsored ADR (ABVX) This Year?
Nov 13, 2025
The Medical group has plenty of great stocks, but investors should always be looking for companies that are outperforming their peers. Has Abivax SA Sponsored ADR (ABVX) been one of those stocks this year? A quick glance at the company's year-to-date performance in comparison to the rest of the Medical sector should help us answer this question.
Abivax SA Sponsored ADR is one of 951 companies in the Medical group. The Medical group currently sits at #4 within the Zacks Sector Rank. The Zacks Sector Rank considers 16 different sector groups. The average Zacks Rank of the individual stocks within the groups is measured, and the sectors are listed from best to worst.
The Zacks Rank is a successful stock-picking model that emphasizes earnings estimates and estimate revisions. The system highlights a number of different stocks that could be poised to outperform the broader market over the next one to three months. Abivax SA Sponsored ADR is currently sporting a Zacks Rank of #2 (Buy).
Over the past three months, the Zacks Consensus Estimate for ABVX's full-year earnings has moved 3.4% higher. This signals that analyst sentiment is improving and the stock's earnings outlook is more positive.
Based on the latest available data, ABVX has gained about 1313% so far this year. In comparison, Medical companies have returned an average of 5.7%. As we can see, Abivax SA Sponsored ADR is performing better than its sector in the calendar year.
Another stock in the Medical sector, Catalyst Pharmaceutical (CPRX), has outperformed the sector so far this year. The stock's year-to-date return is 9.2%.
Over the past three months, Catalyst Pharmaceutical's consensus EPS estimate for the current year has increased 8.3%. The stock currently has a Zacks Rank #2 (Buy).
Breaking things down more, Abivax SA Sponsored ADR is a member of the Medical - Biomedical and Genetics industry, which includes 469 individual companies and currently sits at #85 in the Zacks Industry Rank. On average, stocks in this group have gained 15.4% this year, meaning that ABVX is performing better in terms of year-to-date returns.
In contrast, Catalyst Pharmaceutical falls under the Medical - Drugs industry. Currently, this industry has 144 stocks and is ranked #83. Since the beginning of the year, the industry has moved +7.5%.
Investors with an interest in Medical stocks should continue to track Abivax SA Sponsored ADR and Catalyst Pharmaceutical. These stocks will be looking to continue their solid performance.
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This article originally published on Zacks Investment Research (zacks.com).
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- 2 Beaten-Down Stocks With Incredible Upside Potential
Aug 3, 2025
Key Points
Viking Therapeutics' work in obesity treatment could lead to significant gains down the line. Recursion Pharmaceuticals could change the way drugs are developed. 10 stocks we like better than Viking Therapeutics ›
Recent history has, once again, demonstrated that relatively small biotech companies can see their shares soar significantly on positive developments. Summit Therapeutics' stock is up by more than 2,000% over the past three years, and Abivax, a France-based drugmaker, is up by more than 800% this year following strong clinical data.
Of course, chasing quick gains is not a reliable investing strategy. But some clinical-stage biotechs could deliver superior returns over the long run, provided their master plans come to fruition.
Here are two examples: Viking Therapeutics(NASDAQ: VKTX) and Recursion Pharmaceuticals(NASDAQ: RXRX). These biotechs, both of which have outperformed the market this year, could have massive upside potential -- but there's also risk involved.Image source: Getty Images.
1. Viking Therapeutics
Viking Therapeutics is looking to carve out a niche in the rapidly growing weight loss market. Although this field promises to be highly competitive, Viking's leading candidate, VK2735, has shown strong results in phase 2 clinical trials and has now entered late-stage studies. The biotech is also developing an oral version of this candidate, which is currently in phase 2 trials.
Viking's shares could soar on positive phase 3 and phase 2 data for these programs. Let's look at the opportunity ahead. According to some analysts, the anti-obesity market is expected to be worth $150 billion by 2035, up from $15 billion in 2024. If Viking can grab even 5% of this total -- $7.5 billion -- that would be amazing for a company with a current market cap of only $3.7 billion.
It's worth noting that VK2735 has been one of the more promising midstage anti-obesity assets to date. So things are looking somewhat hopeful for the mid-cap biotech, though a lot will depend on upcoming data readouts.
Beyond Viking's work in weight management, the company has another exciting asset in VK2809, a potential therapy for metabolic dysfunction-associated steatohepatitis (MASH). It has completed phase 2 studies and should move on relatively soon. There's a significant need for more MASH therapies, considering that the disease affects millions of people. Yet the U.S. Food and Drug Administration (FDA) just approved the first therapy specifically for it last year.
Investors have sold off Viking Therapeutics' shares in the past year, but the biotech did nothing wrong. It's a case of shareholders taking profits after the stock soared on strong midstage data, coupled with general market volatility. However, between Viking's work in MASH and its anti-obesity efforts, the stock could recover and deliver monster returns in the next five years if it can record consistent clinical and regulatory success.
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2. Recursion Pharmaceuticals
Recursion Pharmaceuticals is a drugmaker with a slightly different value proposition: It aims to usher in a paradigm shift in the biotech industry. The process to develop medicines is costly, lengthy, and risky. Even if a new chemical entity performs well in animal models during preclinical testing, unforeseen safety issues can arise once it's used on humans -- or it may simply not be as effective as it was in, say, mice.
Recursion is looking to change that thanks to an operating system (OS) powered by artificial intelligence (AI) that tests compounds against a library of genes, and sends only the most promising to clinical studies. Significantly improving the probability that therapies entering clinical trials ultimately reach the market, while reducing the time it takes for them to progress from preclinical to clinical stages, would lead to substantial cost savings for drugmakers. That's Recursion's plan: If its OS can do what it claims, it will license it out to competitors.
The biotech even scored a major win earlier this year when the FDA announced plans to slowly phase out animal testing in favor of other methods, including AI-based models.
Why, then, isn't the company performing well? Recursion Pharmaceuticals has no products on the market and none in phase 3 studies. In other words, it has yet to prove that its technology actually delivers on its promises. If Recursion can demonstrate the value of its platform, its shares will skyrocket.
However, the stock is a high-risk, high-reward play, so only those with a large appetite for risk should consider it. And even then, it's best to start by initiating a small position in the company.
Should you buy stock in Viking Therapeutics right now?
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Prosper Junior Bakiny has positions in Recursion Pharmaceuticals and Viking Therapeutics. The Motley Fool has positions in and recommends Summit Therapeutics. The Motley Fool recommends Viking Therapeutics. The Motley Fool has a disclosure policy.
2 Beaten-Down Stocks With Incredible Upside Potential was originally published by The Motley Fool
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- This Stock Is Up by 800% This Year -- but Is It a Buy?
Jul 31, 2025
Key Points
Abivax's shares skyrocketed following positive clinical trial results for its lead candidate, obefazimod. This investigational medicine could prove more effective than existing drugs for ulcerative colitis. There might be plenty of upside left if obefazimod produces more positive results in further trials. 10 stocks we like better than Abivax Société Anonyme ›
If you had invested money in Abivax(NASDAQ: ABVX) at the beginning of the year, you would be sitting pretty right now. The French biotech's shares recently skyrocketed and are up more than 800% year to date. As investors can probably guess, Abivax's gains are tied to impressive clinical progress for its leading pipeline candidate.
However, some might worry that it's too late to buy the stock now. Is that the case? Let's look deeper into what's going on with Abivax and determine whether there's any upside left.
A potential first-in-class drug
Abivax's leading pipeline candidate is called obefazimod, a potential treatment for ulcerative colitis (UC). It could be a first-in-class drug, meaning a medicine that has a novel mechanism of action distinct from those of existing therapies targeting the same condition. First-in-class drugs sometimes prove more effective than standard existing treatments, so there is significant potential for a smaller biotech company working on a medicine like this one, if it can ace clinical trials.Image source: Getty Images.
Abivax has just achieved exactly that, with strong results from a pair of phase 3 trials for obefazimod. The medicine led to a high rate of remission among participants with moderate to severely active UC, compared to a placebo. Importantly, the studies included patients who had never received any advanced therapy for UC, as well as some who had but had previously failed to achieve remission. According to Abivax, 47.3% of participants in these trials had an inadequate response to prior therapy.
In other words, obefazimod succeeded in helping some patients achieve remission where other medicines had failed. And this isn't an obscure therapeutic area with just a couple of options, either: It's actually a highly competitive market. There are numerous advanced therapies for UC, including some produced by several of the world's largest pharmaceutical companies. That makes obefazimod's success all the more impressive.
Why it may not be too late to buy the stock
Abivax's market capitalization is now 3.7 billion euros (about $4.3 billion). Some analysts estimate that obefazimod could hit peak sales of about $4 billion. Of course, it won't get there anytime soon, even if it earns approval. Though the data looks strong so far, there is more to come.
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The recent results Abivax shared were from induction trials (to see whether a medicine can reduce the symptoms of a disease). The biotech has an ongoing maintenance study (to check whether it can keep the disease under control), the results of which it plans to share in the second quarter of 2026. If this data isn't up to Wall Street's liking, Abivax's shares might plunge.
That's to say nothing of potential regulatory setbacks, which aren't that rare with smaller biotech companies and could also sink the company's stock price. So there are some risks involved, but the stock might be worth it for those who can stomach the volatility. Abivax has developed a medicine with a novel mechanism of action that performs well in clinical trials, and that ability speaks volumes about the company's innovative capabilities.
Meanwhile, although funding was an issue at the start of the year, it should no longer be a problem. Abivax ended the first quarter with 103.6 million euros in cash ($120.1 million), which management thought would only last until the end of this year. Thanks to obefazimod's phase 3 results and the company's stock price soaring, Abivax announced a secondary offering, during which it expects to generate gross proceeds of 637.5 million euros ($747.5 million). That should be plenty of money for the company to keep the lights on, even beyond next year.
There's still significant upside left if the ongoing phase 3 clinical trials for obefazimod in UC also yield strong results. Additionally, Abivax is testing its lead candidate as a monotherapy for Crohn's disease, as well as a potential combination treatment for UC.
Consistent positive clinical and regulatory developments could lead to even more gains for patient investors. That's why it might still be time for those with above-average risk tolerance to initiate a small position in the stock.
Should you buy stock in Abivax Société Anonyme right now?
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Prosper Junior Bakiny has no position in any of the stocks mentioned. The Motley Fool has no position in any of the stocks mentioned. The Motley Fool has a disclosure policy.
This Stock Is Up by 800% This Year -- but Is It a Buy? was originally published by The Motley Fool
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- Rocket lays off staff; Abivax capitalizes on immune drug data
Jul 24, 2025
This story was originally published on BioPharma Dive. To receive daily news and insights, subscribe to our free daily BioPharma Dive newsletter.
Today, a brief rundown of news involving Rocket Pharmaceuticals and Atara Biotherapeutics, as well as updates from Abivax, Gate Bioscience and Matchpoint Therapeutics that you may have missed.
Rocket Pharmaceuticals is laying off approximately 30% of its workforce and focusing resources on gene therapies for three inherited heart conditions, the company said Thursday. Rocket expects the cuts will reduce its operating expenses by one-quarter, which, together with existing cash reserves and the potential sale of a regulatory fast pass it might receive in the future, should help keep the company afloat into the second quarter of 2027. The Food and Drug Administration last year rejected an approval application for Rocket’s gene therapy Kresladi, which the company hopes to resubmit. Rocket said it anticipates delays in advancing two other programs for Fanconi anemia and and pyruvate kinase deficiency. — Ned Pagliarulo
Atara Biotherapeutics and partner Pierre Fabre Pharmaceuticals are taking a second shot at FDA approval of their T cell immunotherapy tab-cel, announcing Thursday that the agency has accepted their resubmission after rejecting an initial attempt over manufacturing in January. The FDA will decide on approval by Jan. 10, Atara said. Tab-cel was developed for previously treated adults and children who have post-transplant lymphoproliferative disease that’s positive for the Epstein-Barr virus. — Ned Pagliarulo
Abivax expects to raise at least $650 million via a sale of its American Depositary shares that it priced Thursday. The secondary stock offering follows the company’s announcement this week of Phase 3 study results for an ulcerative colitis drug that impressed analysts and investors. Should the investment banks underwriting the offering exercise their options to purchase additional stock, Abivax could bring in nearly $750 million, which would be some ten times its current cash holdings. It expects the new funds will give it operating runway through 2027 and support further testing of the drug, obefazimod, in inflammatory bowel disease. — Ned Pagliarulo
Gate Bioscience, a California-based biotechnology company, announced Thursday that it has entered into collaboration and licensing agreement with Eli Lilly. The deal includes an upfront payment, equity investment, and could also hold potential milestone and royalty payouts. A Gate spokesperson said the fresh funding provides more than a year of runway for the company and, all told, the deal value could reach up to $856 million. The company is backed by well-known life sciences investors like Versant Ventures, a16z, Arch Venture Partners and Alphabet's venture capital arm. It aims to create "molecular gates," a new class of medicines designed to stop cells from secreting disease-causing proteins. Through their collaboration, Lilly and Gate hope to identify therapies that can eliminate "specific difficult-to-drug proteins" and thereby provide novel ways to treat diseases with "high unmet medical need." — Jacob Bell
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Privately held Matchpoint Therapeutics is getting validation of its drug research from Novartis, which has agreed to pay the Watertown, Massachusetts-based biotech as much as $60 million in upfront and research funding fees. Under the deal, Matchpoint is responsible for advancing an undisclosed program through preclinical testing, at which point Novartis holds an option to exclusively license it. Matchpoint specializes in drugs that work by binding covalently to their target, and is taking aim at an unnamed transcription factor involved in inflammatory disease. — Ned Pagliarulo
GSK will have to wait a little longer to learn whether its multiple myeloma drug Blenrep can make a return to the U.S. market. The FDA was set to decide on approval by July 23, but extended its review by three months to "review additional information" the company provided to support its application. Blenrep's new decision date is Oct. 23. An advisory committee voted last week that GSK's trial data did not prove a favorable benefit-risk balance for the patients the company hopes to treat. — Ned Pagliarulo
Recommended Reading
GSK prepares to relaunch Blenrep; Activists challenge another ‘zombie’ biotech
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- Abivax Announces Launch of Public Offering
Jul 23, 2025
Abivax
Abivax Announces Launch of Public Offering
PARIS, France, July 23, 2025 – 10:15 p.m. (CEST) – Abivax SA (Euronext Paris: FR0012333284 – ABVX) (“Abivax” or the “Company”), a clinical-stage biotechnology company focused on developing therapeutics that harness the body’s natural regulatory mechanisms to modulate the immune response in patients with chronic inflammatory diseases, announced today the launch of an approximately $400 million underwritten public offering (representing approximately €340 million) consisting of a public offering of its American Depositary Shares (“ADSs”), each representing one ordinary share, €0.01 nominal value per share (each an “Ordinary Share”), of the Company in the United States (the “Offering”). In connection with the Offering, the Company intends to grant the underwriters for the Offering a 30-day option to purchase additional ADSs, in an amount of up to 15% of the total number of ADSs proposed to be sold in the Offering, on the same terms and conditions.
All securities to be sold in the Offering will be offered by the Company. The Company’s ADSs are listed on the Nasdaq Global Market under the ticker symbol “ABVX.” The Company’s Ordinary Shares are listed on the regulated market of Euronext in Paris (“Euronext”) under the symbol “ABVX.”
Leerink Partners, Piper Sandler & Co. and Guggenheim Securities are acting as joint bookrunning managers for the Offering. LifeSci Capital is acting as lead manager, with BTIG and Van Lanschot Kempen acting as co-managers for the Offering.
The ADSs to be sold in the Offering will be issued by way of a capital increase without shareholders’ preferential subscription rights through a public offering (to the exception of public offerings defined in Article L.411-2 1° of the French Monetary and Financial Code (Code monétaire et financier)) in accordance with the 22nd and 27th resolutions of the Company’s combined shareholders’ general meeting held on June 6, 2025 (the “General Meeting”).
The Offering is subject to market conditions and there can be no assurance as to whether or when the Offering may be completed or the actual size or terms of the Offering. The final amount of the Offering, the offering price in the Offering in U.S. dollars, as well as the final number of ADSs sold in the Offering will be determined following a book-building process commencing immediately on the date hereof. The Company will announce the results of the Offering as well as the number and subscription price of ADSs to be issued in the context of the Offering as soon as practicable after pricing thereof in a subsequent press release.
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The trading of Abivax’s Ordinary Shares on Euronext is expected to be suspended on July 24, 2025 until the opening of trading of Abivax’s ADSs on the Nasdaq Global Market at approximately 3:30 pm (Paris time) / 9:30 a.m. (New York time) on July 24, 2025, prior to which Abivax is expected to publish the allocation of share capital to be effective following settlement and delivery of the securities sold in the Offering.
The number of securities to be sold in the Offering will be determined by the Chief Executive Officer of the Company acting upon subdelegation from the Company’s Board of Directors in accordance with the delegation granted by the General Meeting, pursuant to its 22nd and 27th resolutions.
The offering price of the ADSs will be in dollars and will be set in compliance with the limitations set forth in the 22nd resolution of the General Meeting (i.e., the offering price may not be less than the weighted average share price on Euronext over a period chosen by the Board of Directors of between three (3) and ninety (90) consecutive trading days preceding the determination of the issue price, possibly reduced, at the discretion of the Board of Directors, by a maximum discount of ten percent (10%)).
The Offering will be subject to an underwriting agreement. The underwriting agreement will not constitute a performance guarantee (garantie de bonne fin) within the meaning of Article L. 225-145 of the French Commercial Code (Code de commerce).
Ordinary Shares underlying ADSs issued in the Offering will be subject to an application for admission to trading on Euronext on the same trading line as the existing Ordinary Shares of the Company currently listed on Euronext, under the same ISIN code FR0012333284.
As of June 30, 2025, the Company had cash and cash equivalents of $71.4 million or €61.0 million (unaudited) allowing it to finance its operating cash flow requirements into the fourth quarter of 2025. The Company intends to use the net proceeds from the Offering, as follows:
approximately 23% to fund the development of obefazimod for Ulcerative Colitis; approximately 5% to fund the development of obefazimod for Crohn’s Disease; and the remainder (approximately 72%) for working capital and for other general corporate purposes, including preparation of commercialization, additional research and development and financing expenses.
The expected use of proceeds represents the Company’s intentions based upon its current plans and business conditions. The Company cannot predict with certainty all of the particular uses for the net proceeds to be received upon the completion of the Offering or the amounts that the Company will actually spend on the uses set forth above. The amounts and timing of the Company’s actual expenditures and the extent of clinical development may vary significantly depending on numerous factors, including the progress of the development efforts, the status of and results from any ongoing clinical trials or clinical trials the Company may commence in the future, as well as any collaborations that the Company may enter into with third parties for its product candidates and any unforeseen cash needs. As a result, the Company’s management will retain broad discretion over the allocation of the net proceeds.
In connection with the Offering, the Company’s board members and executive officers are subject to a contractual lock-up for a period of 60 days after the date of the final prospectus supplement, subject to customary exceptions. The Company will also agree to be bound by a contractual lock-up for a period of 60 days after the date of the final prospectus supplement, subject to customary exceptions.
An automatic shelf registration statement on Form F-3 (including a prospectus) relating to the Company’s securities was filed with the Securities and Exchange Commission (the “SEC”) on July 23, 2025 and became effective upon filing. The Company intends to file with the SEC a preliminary prospectus supplement (and accompanying prospectus) relating to and describing the terms of the Offering (the “Preliminary Prospectus Supplement”). Before purchasing ADSs in the Offering, potential investors should read the Preliminary Prospectus Supplement (and the accompanying prospectus) together with the documents incorporated by reference therein. These documents may be obtained free of charge by visiting EDGAR on the SEC’s website at www.sec.gov. Alternatively, a copy of the Preliminary Prospectus Supplement (and accompanying prospectus) may be obtained from Leerink Partners LLC, Attention: Syndicate Department, 53 State Street, 40th Floor, Boston, MA 02109, by telephone at (800) 808-7525, ext. 6105, or by email at syndicate@leerink.com; or from Piper Sandler & Co., 800 Nicollet Mall, J12S03, Minneapolis, MN 55402, Attention: Prospectus Department, by telephone at 800-747-3924 or by email at prospectus@psc.com; or from Guggenheim Securities, LLC, Attention: Equity Syndicate Department, 330 Madison Avenue, 8th Floor, New York, NY 10017, by telephone at (212) 518-9544 or by email at GSEquityProspectusDelivery@guggenheimpartners.com.
The Offering is not subject to a prospectus requiring an approval of the AMF.
Potential investors should carefully consider the risks described under “Risk Factors” in the Preliminary Prospectus Supplement, including the following risks:
Our management will have broad discretion over the use of the proceeds from this offering and may apply these proceeds in ways that may not increase the value of your investment; If you purchase ordinary shares or ADSs in the offering, you will experience substantial and immediate dilution; Future sales of ordinary shares or ADSs by existing shareholders could depress the market price of the ADSs and ordinary shares; and Raising additional capital, including as a result of this offering or of further offerings to finance the clinical programs or the commercialization of the Company’s candidate drugs, may cause dilution to our shareholders, restrict our operations or require us to relinquish rights to our product candidates.
In addition, the Company draws attention to the risk factors related to the Company and its activities described under the caption “Risk Factors” in the Preliminary Prospectus Supplement and in the documents incorporated by reference therein and presented in Chapter 2 of the 2025 universal registration document filed with the French Financial Markets Authority (Autorité des Marchés Financiers – the “AMF”) under number D.25-0141 on March 24, 2025, which is available free of charge on the Company’s website at https://ir.abivax.com/fr, as well as on the AMF’s website at www.amf-france.org.
The Company also received on July 23, 2025 a notice from entities affiliated with Heights Capital Management, which hold amortizing senior convertible notes of the Company issued in August 2023 (the “ConvertibleNotes”), for the conversion of 150 Convertible Notes (corresponding to an outstanding principal amount of approximately €9.4 million) into 394,447 new Ordinary Shares of the Company at a conversion price of €23.7674 per Ordinary Share in accordance with the terms and conditions of the Convertible Notes. The corresponding issuance is expected to occur on or about July 29, 2025.
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About Abivax
Abivax is a clinical-stage biotechnology company focused on developing therapeutics that harness the body’s natural regulatory mechanisms to stabilize the immune response in patients with chronic inflammatory diseases. Based in France and the United States, Abivax’s lead drug candidate, obefazimod (ABX464), is in Phase 3 clinical trials for the treatment of moderately to severely active ulcerative colitis.
Contacts:
Abivax Investor Relations
Patrick Malloy
patrick.malloy@abivax.com
+1 847 987 4878
***
Forward-Looking Statements
This press release contains forward-looking statements, forecasts and estimates, including those relating to the Company’s business and financial objectives. Words such as “design,” “intend,” “expect,” “forward,” “future,” “can,” “could,” “may,” “might,” “potential,” “plan,” “project,” “should,” “will” and variations of such words and similar expressions are intended to identify forward-looking statements. These forward-looking statements include statements regarding the completion, timing and size of the Offering, use of net proceeds from the Offering, as well as statements concerning or implying the therapeutic potential of Abivax's drug candidates, clinical development plans, business and regulatory strategy, and anticipated future performance and other statements that are not historical fact. Although Abivax’s management believes that the expectations reflected in such forward-looking statements are reasonable, investors are cautioned that forward-looking information and statements are subject to various risks, contingencies and uncertainties, many of which are difficult to predict and generally beyond the control of Abivax, that could cause actual results and developments to differ materially from those expressed in, or implied or projected by, the forward-looking information and statements. A description of these risks, contingencies and uncertainties can be found in the documents filed by the Company with the AMF pursuant to its legal obligations including its universal registration document (Document d’Enregistrement Universel), and in the Company’s Annual Report on Form 20-F filed with the U.S. Securities and Exchange Commission on March 24, 2025 under the caption “Risk Factors.” These risks, contingencies and uncertainties include among other things, the uncertainties inherent in research and development, future clinical data and analysis, decisions by regulatory authorities, such as the FDA or the EMA, regarding whether and when to approve any drug candidate, as well as their decisions regarding labelling and other matters that could affect the availability or commercial potential of such product candidates and the availability of funding sufficient for the Company’s foreseeable and unforeseeable operating expenses and capital expenditure requirements. Special consideration should be given to the potential hurdles of clinical and pharmaceutical development including further assessment by the Company and regulatory agencies and IRBs/ethics committees following the assessment of preclinical, pharmacokinetic, carcinogenicity, toxicity, CMC and clinical data. Furthermore, these forward-looking statements, forecasts and estimates are made only as of the date of this press release. Readers are cautioned not to place undue reliance on these forward-looking statements. Abivax disclaims any obligation to update these forward-looking statements, forecasts or estimates to reflect any subsequent changes that the Company becomes aware of, except as required by law. Information about pharmaceutical products (including products currently in development) that is included in this press release is not intended to constitute an advertisement. This press release does not give and should not be treated as giving investment advice. It has no connection with the investment objectives, financial situation or specific needs of any recipient. It should not be regarded by recipients as a substitute for exercise of their own judgment. All opinions expressed herein are subject to change without notice.
Disclaimers
This press release does not constitute an offer to sell or the solicitation of an offer to buy any securities of the Company, nor shall there be any sale of such securities, in any state or jurisdiction in which such offer, solicitation or sale would be unlawful prior to registration or qualification under the securities laws of any such state or jurisdiction.
The distribution of this press release may be subject to legal or regulatory restrictions in certain jurisdictions. Any person who comes into possession of this press release must inform him or herself of and comply with any such restrictions.
This announcement is not a prospectus within the meaning of the Prospectus Regulation.
In relation to each member state of the European Economic Area (each, a “Relevant Member State”), an offer of the securities referred to herein is not being made and will not be made to the public in that Relevant Member State, other than (i) to any legal entity which is a qualified investor as defined in the Prospectus Regulation, (ii) to fewer than 150 natural or legal persons per Relevant Member State; or (iii) in any other circumstances falling within Article 1(4) of the Prospectus Regulation; provided that no such offer of the securities referred to herein shall require the Company to publish a prospectus pursuant to Article 3 of the Prospectus Regulation. For the purposes of the above, the expression an “offer to the public” in any Relevant Member State shall have the meaning ascribed to it in Article 2(d) of the Prospectus Regulation.
This communication is being distributed only to, and is directed only at (a) persons outside the United Kingdom, (b) persons who have professional experience in matters relating to investments falling within Article 19(5) of the Financial Services and Markets Act 2000 (Financial Promotion) Order 2005 (the “Order”), and (c) high net worth entities, and other persons to whom it may otherwise lawfully be communicated, falling within Article 49(2) of the Order (all such persons together being referred to as “relevant persons”). Any investment or investment activity to which this communication relates is available only to relevant persons and will be engaged in only with relevant persons. Any person who is not a relevant person should not act or rely on this communication or any of its contents.
Solely for the purposes of each manufacturer’s product approval process, the target market assessment in respect of the securities offered in the Offering has led to the conclusion in relation to the type of clients criteria only that: (i) the type of clients to whom the securities are targeted is eligible counterparties and professional clients only, each as defined in Directive 2014/65/EU, as amended (“MiFID II”); and (ii) all channels for distribution of the securities offered in the Offering to eligible counterparties and professional clients are appropriate. Any person subsequently offering, selling or recommending the Ordinary Shares (a “distributor”) should take into consideration the manufacturers’ type of clients assessment; however, a distributor subject to MiFID II is responsible for undertaking its own target market assessment in respect of the Ordinary Shares offered in the Offering (by either adopting or refining the manufacturers’ type of clients assessment) and determining appropriate distribution channels.
This press release has been prepared in both French and English. In the event of any discrepancies between the two versions of the press release, the French language version shall prevail.
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- Abivax Hits The Stratosphere, Up 500%, On 'Potentially Disruptive' Results
Jul 23, 2025
Shares of Abivax hit the stratosphere Wednesday after the firm unveiled "potentially disruptive" results for its ulcerative colitis drug.
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- Abivax Announces the Appointment of June Lee, M.D. and Troy Ignelzi as Members of the Board of Directors
Jul 11, 2023
PARIS, FRANCE / ACCESSWIRE / July 11, 2023 / Abivax SA (Euronext Paris: FR0012333284 - ABVX), a Phase 3 clinical-stage biotechnology company focused on developing therapeutics that modulate the immune system to treat patients with chronic inflammatory diseases, announces today the appointment of June Lee, M.D. and Troy Ignelzi as new independent members of the Abivax Board of Directors. June Lee and Troy Ignelzi replace Joy Amundson and Jean-Jacques Bertrand, who have resigned from their positions as members of the Board of Directors.
Marc de Garidel, CEO of Abivax, said:"I am glad to welcome June Lee and Troy Ignelzi as new Abivax Board members. As we advance our Phase 3 program with obefazimod in ulcerative colitis, their extensive expertise in late-stage development, product commercialization and financing will be precious for the company to successfully execute on our strategic priorities. On behalf of the entire team, I would also like to warmly thank Joy Amundson and Jean-Jacques Bertrand for their longstanding commitment and contribution. We are now very much looking forward to continuing our work with June and Troy and to benefit from their vast experience in the biopharma industry."
June Lee, M.D., new member of the Abivax Board and Chair of the Recruitment and Remuneration Committee, added:"I am excited to join the Abivax Board and I am impressed by the accomplishments and the clinical results generated so far with obefazimod. Together with the team, we will continue our efforts to further advance this promising drug candidate towards the market for the benefit of all the patients suffering from inflammatory conditions."
Troy Ignelzi, new member of the Abivax Board and Chair of the Audit Committee, commented:"I look forward to working alongside my fellow Board members and the talented Abivax team as we continue to build a compelling company story going forward. I am eager to leverage my knowledge and experience to help enable Abivax to successfully realize its full potential in the discovery, development and commercialization of novel and long-term efficient treatments against chronic inflammatory diseases."
In the frame of the new appointments, the composition of the Board's committees has been reviewed. The Audit Committee is comprised of three members: Troy Ignelzi (Chair), Corinna zur Bonsen-Thomas and Sofinnova Partners (represented by Kinam Hong). The Recruitment and Remuneration Committee is comprised of four members: June Lee (Chair), Corinna zur Bonsen-Thomas, Truffle Capital (represented by Philippe Pouletty) and Sofinnova Partners (represented by Kinam Hong).
About June Lee, M.D.
June H. Lee, M.D. FACCP, is currently a Venture Partner at 5AM Ventures. Dr. Lee is a physician-scientist with over 20 years in the biotechnology and pharmaceutical industry. Most recently, she was a Founder and CEO of Esker Therapeutics. She previously served as Executive Vice President, Chief Development Officer and Chief Operating Officer of MyoKardia where she built and led a world-class development organization that was acquired by Bristol Myers Squibb for USD 13.1 billion in November 2020. The lead program at MyoKardia, mavacamten, was recently approved by the FDA for use in obstructive hypertrophic cardiomyopathy patients as the first precision therapy in this indication. Prior to MyoKardia, Dr. Lee was a Professor of Medicine at the University of California, San Francisco (UCSF) School of Medicine, where she served as Director of Translational Research and built the Catalyst Program, an internal accelerator for early-stage technologies. As the therapeutic area head at Genentech, Dr. Lee led early clinical development programs in cardiovascular and metabolic diseases, infectious diseases, and respiratory diseases. Dr. Lee serves on numerous boards in the healthcare industry including the Board of Directors for Tenaya Therapeutics, Eledon Pharmaceuticals Inc. and GenEdit, and is a member of the Scientific Advisory Board for Foresite Labs. Dr. Lee has also served on the Advisory Board for Johns Hopkins University Center for Therapeutic Translation, and on the Board of Directors for CinCor Therapeutics, which was acquired by AstraZeneca for up to USD 1.8 billion in the first quarter of 2023. Dr. Lee received her undergraduate degree in chemistry at the Johns Hopkins University, earned her medical degree at the School of Medicine at University of California, Davis, and completed her clinical training in internal medicine and pulmonary and critical care at the University of California, Los Angeles (UCLA) and University of California, San Francisco (UCSF). Dr. Lee is based in the San Francisco, CA office.
About Troy Ignelzi
Troy Ignelzi has extensive experience leading emerging and rapidly growing biopharmaceutical company finance and operations, including raising capital and building high-performing teams. He currently serves as the CFO of Karuna Therapeutics, where he is responsible for finance, including business support planning for the company's R&D and commercial preparation. In this role, Mr. Ignelzi has led Karuna's private and public financings, including multiple securities offerings, and developed the financial and operational business support infrastructure required for a public company. Before joining Karuna, Mr. Ignelzi was similarly successful at two other emerging biopharmaceutical companies, Esperion Therapeutics and scPharmaceuticals, where he led multiple private and public financings and developed the financial infrastructure and development strategies to support a public company and ensure long-term financial health. Earlier in his career, Mr. Ignelzi served in a variety of positions, including finance, business development and strategic planning, at Pharmalex, scPharmaceuticals, and Insys Therapeutics, as well as sales at Eli Lilly & Co. Mr. Ignelzi currently serves as the Chairman of the Board of Vedanta Biosciences and previously served as a member of the Board of Directors of CinCor Pharma (acquired by AstraZeneca). He earned his B.S. in Accounting at Ferris State University in Big Rapids, Michigan, U.S.
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About Abivax(www.abivax.com)
Abivax is a Phase 3 clinical stage biotechnology company, focused on developing therapeutics that modulate the immune system to treat patients with chronic inflammatory diseases. Abivax, founded by Truffle Capital, is listed on Euronext compartment B (ISIN: FR0012333284 - Mnémo: ABVX). Based in Paris and Montpellier, Abivax's lead drug candidate, obefazimod (ABX464), is in Phase 3 clinical trials for the treatment of ulcerative colitis. More information on the Company is available at www.abivax.com . Follow us on Twitter @ABIVAX_.
Contacts
Abivax
Communications
Regina Jehle
regina.jehle@abivax.com
+33 6 24 50 69 63 Investors
LifeSci Advisors
Ligia Vela-Reid
lvela-reid@lifesciadvisors.com
+44 7413 825310 Press Relations & Investors Europe
MC Services AG
Anne Hennecke
anne.hennecke@mc-services.eu
+49 211 529 252 22 Public Relations France
Actifin
Ghislaine Gasparetto
ggasparetto@actifin.fr
+33 6 21 10 49 24 Public Relations France
Primatice
Thomas Roborel de Climens
thomasdeclimens@primatice.com
+33 6 78 12 97 95 Public Relations USA
Rooney Partners LLC
Jeanene Timberlake
jtimberlake@rooneypartners.com
+1 646 770 8858
DISCLAIMER
This press release contains forward-looking statements, forecasts and estimates with respect to certain of the company's programs. Although Abivax' management believes that the expectations reflected in such forward-looking statements are reasonable, investors are cautioned that forward-looking information and statements are subject to various risks, contingencies and uncertainties, many of which are difficult to predict and generally beyond the control of Abivax, that could cause actual results and developments to differ materially from those expressed in, or implied or projected by, the forward-looking information and statements. A description of these risks, contingencies and uncertainties can be found in the documents filed by the company with the French Autorité des Marchés Financiers pursuant to its legal obligations including its registration document (Document d'Enregistrement Universel). These risks, contingencies and uncertainties include among other things, the uncertainties inherent in research and development, future clinical data and analysis, decisions by regulatory authorities, such as the FDA or the EMA, regarding whether and when to approve any drug, as well as their decisions regarding labelling and other matters that could affect the availability or commercial potential of such product candidates. Special consideration should be given to the potential hurdles of clinical and pharmaceutical development including further assessment by the company and regulatory agencies and IRBs/ethics committees following the assessment of preclinical, pharmacokinetic, carcinogenicity, toxicity, CMC and clinical data. Furthermore, these forward-looking statements, forecasts and estimates are only as of the date of this press release. Readers are cautioned not to place undue reliance on these forward-looking statements. Abivax disclaims any obligation to update these forward-looking statements, forecasts or estimates to reflect any subsequent changes that the company becomes aware of, except as required by law. Information about pharmaceutical products (including products currently in development) which is included in this press release is not intended to constitute an advertisement. This press release is for information purposes only, and the information contained herein does not constitute either an offer to sell, or the solicitation of an offer to purchase or subscribe securities of the company in any jurisdiction, in particular in France. Similarly, it does not give and should not be treated as giving investment advice. It has no connection with the investment objectives, financial situation or specific needs of any recipient. It should not be regarded by recipients as a substitute for exercise of their own judgement. All opinions expressed herein are subject to change without notice. The distribution of this document may be restricted by law in certain jurisdictions. Persons into whose possession this document comes are required to inform themselves about and to observe any such restrictions.
SOURCE: ABIVAX
View source version on accesswire.com:
https://www.accesswire.com/766929/Abivax-Announces-the-Appointment-of-June-Lee-MD-and-Troy-Ignelzi-as-Members-of-the-Board-of-Directors
- Abivax receives "Capital Market Transaction of the Year Award" at the European Mediscience Awards 2023
Jun 15, 2023
The award recognizes a significant capital market transaction in the biotech sector Abivax received the award for its oversubscribed EUR 130M cross-over financing at market price with top-tier US and European Biotech investors in February 2023
PARIS, FRANCE / ACCESSWIRE / June 15, 2023 / Abivax (Euronext Paris:FR0012333284 - ABVX), a Phase 3 clinical-stage biotechnology company focused on developing therapeutics that modulate the immune system to treat patients with chronic inflammatory diseases, announces today that it received the "Capital Market Transaction of the Year Award" at the European Mediscience Awards 2023. This award recognizes a significant capital market transaction taking into account the amount of money raised, stock price performance and the quality of the share register.
Abivax received the award for its EUR 130M oversubscribed capital increase at market price in February 2023. The financing round was led by TCGX, with participation from existing investors such as Sofinnova Partners, Invus, Deep Track Capital, Venrock Healthcare Capital Partners, as well as from new investors such as Great Point Partners LLC, Deerfield Management Company, Commodore Capital, Samsara BioCapital, Boxer Capital and others.
Didier Blondel, CFO of Abivax, said: "We are proud and feel honored to receive the "Capital Market Transaction of the Year Award" at the European Mediscience Awards 2023. We were very pleased that Abivax could attract top-tier U.S. and European biotech investors for this transaction which, we believe, is a valuable recognition of the remarkable clinical achievements with obefazimod during the past months and years. The Company's strategic priority at present is the completion of our global Phase 3 clinical program of obefazimod for the treatment of ulcerative colitis. The entire Abivax team stays committed to bringing obefazimod to the market for the benefit of the many UC patients in need of safe and long-term efficient treatment options."
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About the European Mediscience Awards 2023
The event is the largest annual gathering of private and publicly quoted healthcare, biotech and life sciences companies in Europe. Bringing together the best of European mediscience companies to celebrate achievement and recognize success. Each year sees the attendance of over 500 public and private European life sciences companies and their corporate advisers, analysts, fund managers, commentators and peers.
About Abivax (www.abivax.com)
Abivax is a Phase 3 clinical stage biotechnology company, focused on developing therapeutics that modulate the immune system to treat patients with chronic inflammatory diseases. Abivax, founded by Truffle Capital, is listed on Euronext compartment B (ISIN: FR0012333284 - Mnémo: ABVX). Based in Paris and Montpellier, Abivax's lead drug candidate, obefazimod (ABX464), is in Phase 3 clinical trials for the treatment of ulcerative colitis. More information on the Company is available at www.abivax.com. Follow us on Twitter @ABIVAX_.
Contacts
Abivax
Communications
Regina Jehle
regina.jehle@abivax.com
+33 6 24 50 69 63 Investors
LifeSci Advisors
Ligia Vela-Reid
lvela-reid@lifesciadvisors.com
+44 7413 825310 Press Relations & Investors Europe
MC Services AG
Anne Hennecke
anne.hennecke@mc-services.eu
+49 211 529 252 22 Public Relations France
Actifin
Ghislaine Gasparetto
ggasparetto@actifin.fr
+33 6 21 10 49 24 Public Relations France
Primatice
Thomas Roborel de Climens
thomasdeclimens@primatice.com
+33 6 78 12 97 95 Public Relations USA
Rooney Partners LLC
Jeanene Timberlake
jtimberlake@rooneypartners.com
+1 646 770 8858
SOURCE: ABIVAX
View source version on accesswire.com:
https://www.accesswire.com/761638/Abivax-receives-Capital-Market-Transaction-of-the-Year-Award-at-the-European-Mediscience-Awards-2023
- Abivax Stock Included in MSCI Indexes
Jun 8, 2023
As of June 1st, the Abivax stock is represented in the MSCI Indexes The MSCI Indexes reflect the evolution of the world's equity markets to support investors building effective portfolios based on risk and return assessments
PARIS, FRANCE / ACCESSWIRE / June 8, 2023 / Abivax (Euronext Paris: FR0012333284 - ABVX), a Phase 3 clinical-stage biotechnology company focused on developing therapeutics that modulate the immune system to treat patients with chronic inflammatory diseases, announces today that as of June 1 st , 2023, its stock is represented in the MSCI Indexes.
MSCI provides decision support tools and services for the global investment community, reflecting the evolution of the world's equity markets and segments. The MSCI Indexes are composed of large, mid and small cap stocks and are predominately used as a benchmark or as a performance reference by actively managed mutual funds or mapped by exchange-traded funds (ETF).
Didier Blondel, CFO of Abivax, said: "The inclusion of the Abivax stock in the MSCI Indexes illustrates the recognition and solidity of our Company, based on liquidity and market capitalization evaluation. It further gives us the opportunity to raise our profile and continue to establish trust with the international investment community."
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About Abivax (www.abivax.com)
Abivax is a Phase 3 clinical stage biotechnology company, focused on developing therapeutics that modulate the immune system to treat patients with chronic inflammatory diseases. Abivax, founded by Truffle Capital, is listed on Euronext compartment B (ISIN: FR0012333284 - Mnémo: ABVX). Based in Paris and Montpellier, Abivax's lead drug candidate, obefazimod (ABX464), is in Phase 3 clinical trials for the treatment of ulcerative colitis. More information on the Company is available at www.abivax.com . Follow us on Twitter @ABIVAX_.
Contacts
Abivax
Communications
Regina Jehle
regina.jehle@abivax.com
+33 6 24 50 69 63 Investors
LifeSci Advisors
Ligia Vela-Reid
lvela-reid@lifesciadvisors.com
+44 7413 825310 Press Relations & Investors Europe
MC Services AG
Anne Hennecke
anne.hennecke@mc-services.eu
+49 211 529 252 22 Public Relations France
Actifin
Ghislaine Gasparetto
ggasparetto@actifin.fr
+33 6 21 10 49 24 Public Relations France
Primatice
Thomas Roborel de Climens
thomasdeclimens@primatice.com
+33 6 78 12 97 95 Public Relations USA
Rooney Partners LLC
Jeanene Timberlake
jtimberlake@rooneypartners.com
+1 646 770 8858
DISCLAIMER
This press release contains forward-looking statements, forecasts and estimates (including patient recruitment) with respect to certain of the Company's programs. Although Abivax' management believes that the expectations reflected in such forward-looking statements are reasonable, investors are cautioned that forward-looking information and statements are subject to various risks, contingencies and uncertainties, many of which are difficult to predict and generally beyond the control of Abivax, that could cause actual results and developments to differ materially from those expressed in, or implied or projected by, the forward-looking information and statements. A description of these risks, contingencies and uncertainties can be found in the documents filed by the Company with the French Autorité des Marchés Financiers pursuant to its legal obligations including its registration document (Document d'Enregistrement Universel). These risks, contingencies and uncertainties include among other things, the uncertainties inherent in research and development, future clinical data and analysis, decisions by regulatory authorities, such as the FDA or the EMA, regarding whether and when to approve any drug, as well as their decisions regarding labelling and other matters that could affect the availability or commercial potential of such product candidates. Special consideration should be given to the potential hurdles of clinical and pharmaceutical development including further assessment by the company and regulatory agencies and IRBs/ethics committees following the assessment of preclinical, pharmacokinetic, carcinogenicity, toxicity, CMC and clinical data. Furthermore, these forward-looking statements, forecasts and estimates are only as of the date of this press release. Readers are cautioned not to place undue reliance on these forward-looking statements. Abivax disclaims any obligation to update these forward-looking statements, forecasts or estimates to reflect any subsequent changes that the Company becomes aware of, except as required by law. Information about pharmaceutical products (including products currently in development) which is included in this press release is not intended to constitute an advertisement. This press release is for information purposes only, and the information contained herein does not constitute either an offer to sell, or the solicitation of an offer to purchase or subscribe securities of the Company in any jurisdiction, in particular in France. Similarly, it does not give and should not be treated as giving investment advice. It has no connection with the investment objectives, financial situation or specific needs of any recipient. It should not be regarded by recipients as a substitute for exercise of their own judgement. All opinions expressed herein are subject to change without notice. The distribution of this document may be restricted by law in certain jurisdictions. Persons into whose possession this document comes are required to inform themselves about and to observe any such restrictions.
SOURCE: ABIVAX
View source version on accesswire.com:
https://www.accesswire.com/760111/Abivax-Stock-Included-in-MSCI-Indexes
